By Pooya Khan Mohammad Beigi, Emanual Maverakis

ISBN-10: 3319178180

ISBN-13: 9783319178189

ISBN-10: 3319178199

ISBN-13: 9783319178196

This new textual content offers perception and remedies for the coated illness, together with dozens of top of the range images, illustrations, and scientific tables. themes coated comprise the background of the illness, different types of the illness, molecular research, epidemiology, results on physique platforms, sickness signs, and therapy. Acrodermatitis Enteropathica is an extraordinary affliction of zinc metabolism that happens in a single of 2 types: inborn and bought. If untreated, the disorder is deadly and affected participants could die inside quite a few years, yet in view that there is not any medication for the situation, it truly is severe that physicians are conscious of the symptoms relating to AE and the perfect remedies to be had for sufferers. A finished consultant to Acrodermatitis Enteropathica is the single e-book of its variety to provide perception into this infrequent sickness. Written by means of and for dermatologists, pediatric experts, and ObGYN’s, this ebook includes one of many greatest medical learn reviews performed on Acrodermatitis Enteropathica during the last decade.​

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Extra info for Acrodermatitis Enteropathica: A Clinician's Guide

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74. Michalczyk AA, et al. Constitutive expression of hZnT4 zinc transporter in human breast epithelial cells. Biochem J. 2002;364(Pt 1):105–13. 75. Zhao H, Eide D. The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation. Proc Natl Acad Sci. 1996;93(6):2454–8. 76. Jiang Y, et al. Genome wide identification, phylogeny and expression of zinc transporter genes in common carp. PLoS One. 2014;9(12), e116043. 77. Martin AB, et al. Gastric and colonic zinc transporter ZIP11 (Slc39a11) in mice responds to dietary zinc and exhibits nuclear localization.

Effect of citrate, glutathione and picolinate on zinc transport by brush border membrane vesicles from rat intestine. J Nutr. 1983;113(8):1653–6. 34. Hurley LS, Lonnerdal B, Stanislowski AG. Zinc citrate, human milk, and acrodermatitis enteropathica. Lancet. 1979;1(8117):677–8. 35. Sang N, et al. Postsynaptically synthesized prostaglandin E2 (PGE2) modulates hippocampal synaptic transmission via a presynaptic PGE2 EP2 receptor. J Neurosci. 2005;25(43):9858–70. 36. Solomons NW, Jacob R. Studies on the bioavailability of zinc in humans: effects of heme and nonheme iron on the absorption of zinc.

Zinc can complex with ZBL and be absorbed as part of a ligand molecule. An increase of the amount of ZBL present would result in a greater quantity of zinc-ZBL ligand complexes and an increase in the amount of zinc absorbed. ZBLs may provide a significant additional route for zinc absorption which may be utilized by the body in the absence or limited presence of zinc absorbing proteins, such as hZip4. It is important to note that this is only a theory based on laboratory and clinical research results.

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Acrodermatitis Enteropathica: A Clinician's Guide by Pooya Khan Mohammad Beigi, Emanual Maverakis


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